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Review Question - QID 213509

Hyper IgE Syndrome / Job Syndrome Introduction Pathogenesis QID: 213509 (M1.OMB.19.1)
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QID 213509 (Type "213509" in App Search)
A 4-year-old boy is brought to the emergency department with 2 days of fever and painful lumps in his legs bilaterally. In addition, he says that his arms and legs are extremely itchy. Since birth he has had recurrent skin and soft tissue infections. Physical exam reveals a pruritic erythematous scaling rash along both upper and lower extremities bilaterally. Palpation of the painful lesions reveal indurated tissue without any production of pus. Which of the following protein functions is most likely disrupted in this patient?
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