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Review Question - QID 212695

Coagulation Cascade Tests PTT (intrinsic pathway) QID: 212695 (M1.OMB.19.1)
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QID 212695 (Type "212695" in App Search)
A 14-year-old boy is brought to the emergency department by his mother after falling from the jungle gym and developing severe left knee pain and swelling. On presentation, he is found to be in pain with a hot, swollen, erythematous left knee. His past medical history is significant for abnormal coagulation lab tests before an appendectomy, but his mother cannot recall the exact details. Coagulation tests are conducted with the following results:

Bleeding time: 3 minutes
Prothrombin time: 11 seconds
Partial thromboplastin time: 53 seconds
Bradykinin formation: decreased

Which of the following factors is most likely defective in this patient?
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