Review Question - QID 212536

A 29-year-old woman comes to the clinic for complaints of fatigue and palpitations for the past 3 days. She reports that even standing up and walking around takes “a lot of energy.” She was forced to call in sick today to her work as a kindergarten teacher. She denies any previous episodes but does endorse symmetric joint pain of her hands, wrists, knees, and ankles that was worse in the morning over the past week that self-resolved. She also reports a runny nose and congestion. Past medical history is unremarkable. Physical examination demonstrates splenomegaly, pallor, and generalized weakness; there is no lymphadenopathy. What is the most likely explanation for this patient’s symptoms?