Review Question - QID 212333

A 52-year-old man presents to his primary care physician for a yearly checkup complaining of recent weight gain. The patient states that he has noticed that, regardless of his diet, his midsection has gotten increasingly larger and his old clothes no longer fit. The patient has a 2-year history of left hip arthritis from a car accident for which he is on prednisone, as well as a history of migraine headaches. The patient has also noticed that in the last 2 months, he has developed acne and his face has become fuller in appearance. On exam, the patient has gained 26 pounds since his previous checkup 1 year prior, and he now has a BMI 28.2 kg/m^2 (up from 24.1 kg/m^2 previously). His temperature is 98.3°F (36.8°C), blood pressure is 134/94 mmHg, pulse is 72/min, and respirations are 12/min. His physical exam is notable for red striae on his shoulders and around his waist. On his labs, the patient’s serum ACTH is found to be decreased. Which of the following changes is most likely expected?