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Review Question - QID 211043

Modes of Inheritance Autosomal Recessive (AR) Generations affected QID: 211043 (M1.OMB.18.4874)
In scope icon M 4 B
QID 211043 (Type "211043" in App Search)
A Caucasian 32-year-old woman has an uncomplicated vaginal delivery, giving birth to male and female fraternal twins at term. At 2 days of life, the twin sister develops abdominal distension without emesis, and the mother states that she has not noticed the passage of stool for this infant. Genetic testing identifies deletion of an amino acid in a membrane channel for the girl. Both parents are healthy. Assuming that twin brother's disease status/symptomatology is unclear, which of the following best approximates the probability that the twin brother is a carrier of the disease allele?
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