Review Question - QID 211011

A 67-year-old woman presents to her primary care physician because she has been feeling increasingly fatigued over the last month. She has noticed that she gets winded halfway through her favorite walk in the park even though she was able to complete the entire walk without difficulty for years. She recently moved to an old house and started a new Mediterranean diet. Her past medical history is significant for hypertension and osteoarthritis for which she underwent a right hip replacement 2 years ago. Physical exam reveals conjunctival pallor as well as splenomegaly. Labs are obtained and the results are shown below:

Hemoglobin: 9.7 g/dL (normal: 12-15.5 g/dL)
Mean corpuscular volume: 91 µm^3 (normal: 80-100 µm^3)
Direct Coombs test: positive
Indirect Coombs test: positive

Peripheral blood smear reveals spherical red blood cells. Red blood cells are also found to spontaneously aggregate at room temperature. The disorder that is most likely responsible for this patient's symptoms should be treated in which of the following ways?