Review Question - QID 210410

A 50-year-old man presents to the emergency room after having a seizure. He has never had a seizure before. His wife accompanies him and reports that he has been experiencing occasional headaches and nausea over the past 6 months that appear to be worsening. His past medical history is notable for hypertension, for which he takes hydrochlorothiazide. He has a 60-pack-year smoking history and drinks 2-3 alcoholic beverages per day. His temperature is 98.6°F (37°C), blood pressure is 125/75 mmHg, pulse is 94/min, and respirations are 18/min. On exam he is lethargic, but able to respond to questions in complete sentences. Reflexes are 2+ and strength is 5/5 bilaterally in the upper and lower extremities. A brain MRI is performed, and a significant finding is shown in Figure A. Which of the following findings would most likely be seen on histological examination of this patient's lesion?