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Review Question - QID 109892

Hypersensitivity Summary QID: 109892 (M1.IM.18.4872)
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QID 109892 (Type "109892" in App Search)
A 9-year-old boy is brought to the emergency room by his mother. She is concerned because her son’s face has been swollen over the past 2 days. Upon further questioning, the boy reports having darker urine without dysuria. The boy was seen by his pediatrician 10 days prior to presentation with a crusty yellow sore on his right upper lip that has since resolved. His medical history is notable for juvenile idiopathic arthritis. His temperature is 99°F (37.2°C), blood pressure is 140/90 mmHg, pulse is 95/min, and respirations are 18/min. On exam, he has mild periorbital edema. Serological findings are shown below:

C2: Normal
C3: Decreased
C4: Normal
CH50: Decreased

Additional workup is pending. This patient most likely has a condition caused by which of the following?
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