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Review Question - QID 109392

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QID 109392 (Type "109392" in App Search)
A 32-year-old woman in Florida presents to your office with abdominal pain and bloating over the last month. She also complains of intermittent, copious, non-bloody diarrhea over the same time. Last month, she first noticed a small rash on her leg, and then developed a cough that has since improved but has not completely resolved. She has no sick contacts and has not left the country recently. Physical examination is notable for a small pink streak on her right leg. Serum laboratory studies are pending. Examination of her stool reveals the causative organism. This organism is most likely transmitted to the human host through which of the following routes?

Inhalation

18%

39/216

Penetration of skin

58%

125/216

Animal bite

12%

26/216

Insect bite

5%

10/216

Sexual contact

5%

11/216

Select Answer to see Preferred Response

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This patient presenting with both pulmonary and abdominal symptoms after a rash is most likely infected with Strongyloides stercoralis, which is transmitted through penetration of the skin.

Strongyloides stercoralis is a roundworm that is transmitted through contact penetration of the skin and is found around the world, including the southeastern United States. The most common route of penetration is through bare feet. The parasite subsequently undergoes blood-borne transmission to the lung, which then results in pulmonary symptoms. Coughing and swallowing the larvae leads to autoinfection of the intestine.

Incorrect Answers:
Answer 1: Inhalation of spores can lead to mycotic infection such as histoplasmosis. The pulmonary findings in Strongyloides are due to blood-borne transmission after initial skin penetration.

Answer 3: Animal bites can transmit some bacteria (such as Pasteurella) and viruses (such as rabies). They are not a common cause of transmission of Strongyloides.

Answer 4: Insect bites, particularly from flies, can lead to roundworm infections such as by Onchocerca volvulus. Strongyloides is not transmitted by insect bites.

Answer 5: Sexual contact is not associated with roundworm infection.

Bullet Summary:
Strongyloides stercoralis is a roundworm that causes both abdominal and pulmonary symptoms and is transmitted to humans through contact penetration of the skin.

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