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Review Question - QID 108775

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QID 108775 (Type "108775" in App Search)
A 27-year-old G1P0 presents to her obstetrician for her normal 30-week obstetric appointment. She reports that she feels well and has no complaints. Her past medical history is notable for intermittent asthma. Her only medications are prenatal vitamins. She has gained 10 pounds, more than expected given her current stage of pregnancy. Abdominal ultrasound reveals the presence of twins with separate amniotic sacs that share a common chorion and placenta. During which time interval following fertilization did the morula divide into two in this mother?

Days 1-3

8%

7/84

Days 4-8

79%

66/84

Days 9-12

11%

9/84

Days 13-15

1%

1/84

Day 16+

0%

0/84

Select Answer to see Preferred Response

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This mother has monochorionic diamnionic twins. In order for twins to share one chorion but have separate amniotic membranes, the morula must divide between 4-8 days after fertilization.

Twin gestations occur when either one oocyte fertilized by one sperm divides into two (monozygotic) or when two oocytes are each fertilized by different sperm (dizygotic). All dizygotic twins (fraternal twins) will be genetically different and will have two amniotic sacs, two chorions, and two placentas. Monozygotic twins are more complex and the number of chorions and amniotic sacs will change depending on when division occurs following fertilization. If the division occurs between days 4 and 8, twins will be share one chorion but have separate amniotic membranes (monochorionic diamniotic). This is the most common variation of identical twins.

Incorrect Answers:
Answer 1: If division occurs between days 1 and 3, twins will be dichorionic diamniotic.

Answer 3: If division occurs between days 9 and 12, twins will be monochorionic monoamniotic.

Answers 4 & 5: If division occurs after day 13, twins will be conjoined.

Bullet Summary:
Monozygotic (identical) twinning occurs when a single morula divides into two. Monochorionic diamniotic twinning is the most common variation of identical twins and will occur if the morula divides between 4 to 8 days after fertilization.

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