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Review Question - QID 107112

Colorectal Cancer (CRC) Introduction Pathogenesis QID: 107112 (M1.ON.15.4666)
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QID 107112 (Type "107112" in App Search)
A 58-year-old male undergoes a surveillance colonoscopy in which a 2 cm adenoma is identified and removed. Had this adenoma not been excised, the patient would have been at risk of progression to carcinoma. Which of the following is the final mutational step in the progression from adenoma to carcinoma?
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