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Review Question - QID 106907

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QID 106907 (Type "106907" in App Search)
A 27-year-old male presents to the emergency room with a chief complaint of bloody diarrhea. He reports feeling lightheaded, with intermittent, severe abdominal pain, and notes that last night for dinner, he ate a hamburger, salad, and a leftover piece of bacon. On exam, his blood pressure is 108/76 mmHg, heart rate is 98 beats per minute, temperature is 99.4 degrees Fahrenheit, and respiratory rate is 12 breaths per minute. Which of the following is LEAST likely to be the cause of his symptoms?

Shigella dysenteriae

7%

13/184

Salmonella enteriditis

7%

12/184

Enterotoxogenic Escherichia coli (ETEC)

65%

120/184

Enterohemorrhagic Escherichia coli (EHEC)

7%

12/184

Yersinia enterocolitica

14%

26/184

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This patient's presentation is consistent with bacterial or viral food poisoning. ETEC causes watery, not bloody, diarrhea.

While nearly all viruses cause watery diarrhea, bacterial infections can manifest with either watery or bloody diarrhea. The differential diagnosis of bloody diarrhea should include S. enteriditis, S. dysenteriae, C. jejuni, Y. enterocolitica, enterohemorrhagic E. coli (EHEC), and C. difficile. While bacterial induced diarrhea is usually associated with meat, dairy, and other foods, viral-induced diarrhea is caused by fecal-oral transmission.

Barr and Smith discuss acute diarrheal illnesses. They note that most cases of diarrhea are caused by viruses, and stool cultures are not recommended for work-up. Treatment is focused on rehydration, and antimotility agents can be used for symptom management in watery diarrhea, but not bloody diarrhea.

Dupont discusses acute infectious diarrhea in immunocompetent adults. He notes that 83% of deaths from diarrheal diseases in the United States occur in adults over 65 years. Most lethal cases occur due to C. difficile or norovirus.

Illustration A shows a colonoscopy depicting C. difficile colitis (also known as pseudomembranous colitis).

Incorrect Answers:
Answer 1: S. dysenteriae causes bloody diarrhea and is transmitted by fecal-oral contamination.
Answer 2: S. enteriditis causes bloody diarrhea and is transmitted through chicken products.
Answer 4: EHEC causes bloody diarrhea and is transmitted transmitted through undercooked meat and fecal-oral contamination.
Answer 5: Y. enterocolitica causes bloody diarrhea and is transmitted through milk, pork, and pet feces.

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