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It is the most common primary brain tumor
24%
34/143
The specimen demonstrates psammoma bodies
13%
19/143
The patient's disease would be consistent with the MRI shown in Figure B
14%
20/143
The tumor arises from arachnoid cells external to the brain
The patient's prognosis is good since the tumor is slow-growing
34%
48/143
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Progressive headaches that are worse in the morning in an elderly patient are concerning for a brain tumor. A chicken-wire capillary pattern and "fried egg" cells are characteristic of oligodendrogliomas, a relatively rare, slow-growing primary brain tumor. Oligodendrogliomas most often occur in the frontal lobes and can be diagnosed based on their chicken-wire, delicate capillary pattern and "fried egg" cells with round nuclei and clear cytoplasm (also described as perinuclear halos). These tumors are also often calcified. Given their slow rate of growth, oligodendrogliomas have a good prognosis when compared with other malignant primary brain tumors. Figure A depicts the "fried egg" and chicken-wire capillary pattern of an oligodendroglioma. Incorrect Answers: Answer 1: The most common primary brain tumor is glioblastoma multiforme, a grade IV astrocytoma. Answer 2: Psammoma bodies are laminated calcifications found in meningiomas. Answer 3: Butterfly gliomas are seen in glioblastoma. Answer 4: Meningiomas arise from arachnoid cells external to the brain.
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