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Review Question - QID 106254

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QID 106254 (Type "106254" in App Search)
A 68-year-old man presents to his primary care physician complaining of bulge in his scrotum that has enlarged over the past several months. He is found to have a right-sided inguinal hernia and proceeded with elective hernia repair. At his first follow-up visit, he complains of a tingling sensation on his scrotum. Which of the following nerve roots communicates with the injured tissues?

L1-L2

36%

80/225

L2-L3

7%

16/225

L4-L5

10%

22/225

S1-S3

17%

38/225

S2-S4

22%

49/225

Select Answer to see Preferred Response

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The genitofemoral nerve, arising from nerve roots L1-L2, is responsible for sensation to the scrotum, and was most likely injured during the hernia repair, as it runs directly through the superficial inguinal ring.

In male subjects, the genitofemoral nerve transits through the superficial inguinal ring adjacent to the spermatic cord and supplies the scrotal skin as well as the cremaster muscle. The ilioinguinal nerve also shares territory here, so an isolated genitofemoral nerve injury should only result in transient anesthesia of the scrotal skin. Similarly, an acute injury to this nerve may result in decreased or absent cremaster reflex.

Bax et al. describe the anatomy and major nerves in the inguinal region: ilioinguinal, iliohypogastric and genitofemoral nerves. The ilioinguinal nerve directly traverses the inguinal canal near the external inguinal ring and provides unilateral sensory innervation to the pubic region and the upper portion of the scrotum or the labia majora. This ilioinguinal nerve is most commonly injured during open herniorrhaphy.

Muto et al. describe inguinal neuralgia after open and laparoscopic hernia as a rare, but well-defined complication occurring in approximately 0.5% of hernia repairs. In some patients, persistent symptoms necessitate further surgical intervention for entrapment of the genitofemoral nerve and ilioinguinal nerve. They describe a personal endoscopic retroperitoneal approach for ilioinguinal and genitofemoral branch neurectomy.

Illustration A shows the lumbar nerve roots and their respective branches. The genitofemoral nerve can be seen extending from L1-L2 nerve roots.
Illustration B shows the sacral plexus. Note that S2-S4 give rise to the pudendal nerve, which innervates the external genitalia.

Incorrect Responses:
Answer 2: L2-L3 give rise to the lateral femoral cutaneous nerve, which innervates the lateral skin of the thigh.
Answer 3: L4-L5 give rise to the lumbosacral trunk.
Answer 4: The posterior femoral cutaneous nerve originates at the S1-S3 nerve roots and is responsible for the skin overlying the buttock.
Answer 5: S2-S4 give rise to the pudendal nerve, which provides sensation to the external genitalia.

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