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Retrospective cohort
14%
31/228
Prospective cohort
44%
100/228
Retrospective case-control
11%
26/228
Prospective case-control
15%
34/228
Cross-sectional study
10%
22/228
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A prospective cohort study identifies a group of people who are exposed and unexposed to some exposure and then follows them in time to see who develops a disease of interest. Observational studies (of which cohort studies are a subtype) can be either prospective or retrospective. Cohort studies compare a group with a given risk factor to a group without the risk factor to see if there is an increased likelihood of developing disease. An example of a cohort study is whether patients who drink alcohol are more likely to get cirrhosis. The computed result of a cohort study is a relative risk value. Illustration A presents the study design of cohort studies, both prospective and retrospective. Incorrect Answers: Answers 1: A retrospective cohort study first groups patients by risk factors and then subsequently looks at their outcomes. Because this study is going forward, it is not retrospective, and data is collected in a prospective manner. Answers 3,4: A case-control study compares the odds of being exposed between patients with disease and patients without the disease. This is not the case in this study either retrospectively or prospectively. Answer 5: A cross-sectional study assesses disease status and exposure/risk factors at the same point in time. It may show association but not causality.
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