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Review Question - QID 100558

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QID 100558 (Type "100558" in App Search)
Figure A shows a pressure-volume loop for the left ventricle. Which of the following changes on the pressure-volume loop best corresponds to stroke volume?
  • A

4 => 1

1%

3/219

1 => 2

32%

70/219

3 => 4

48%

106/219

2 => 3

10%

21/219

Stroke volume can not be calculated from this diagram

7%

15/219

  • A

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In the pressure-volume loop shown, movement from point 3 to point 4 corresponds to the stroke volume. Stroke volume is the total amount of blood that is ejected from the left ventricle (LV) during left ventricle contraction. At the end of isovolumetric contraction (point 3) the aorta opens and blood leaves the left ventricle until it closes (point 4) and isovolumetric relaxation begins.

Stroke volume (SV) can be calculated using the following equation:
SV = End Diastolic Volume - End Systolic Volume

Therefore, SV is dependent on diastolic filling (point 1 to point 2) and systolic ejection (point 3 to point 4). During ventricular filling, the mitral valve is open, while the aortic valve is closed. During ejection, the mitral valve is closed, while the aortic valve is open. See Illustration A.

Incorrect Answers:
Answer 1: 4 => 1 corresponds to isovolumetric relaxation.
Answer 2: 1 => 2 corresponds to ventricular filling. The mitral valve is open at this time.
Answer 4: 2 => 3 corresponds to the period isovolumetric contraction of the ventricle while all valves are closed.
Answer 5: The stroke volume can be calculated from this exam and is demonstrated by movement from 3 to 4.

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