Select a Community
Are you sure you want to trigger topic in your Anconeus AI algorithm?
You are done for today with this topic.
Would you like to start learning session with this topic items scheduled for future?
Membrane attack complex formation is impaired
6%
50/872
Opsonization and phagocytosis of pathogen cannot occur
8%
67/872
Impaired adaptive immune system memory
1%
13/872
Impaired antibody binding to mast cells
2%
14/872
Impaired mucosal immune protection
81%
710/872
Select Answer to see Preferred Response
Neisseria gonorrhoeae and Neisseria meningitidis both produce a protease capable of cleaving IgA molecules. This results in impaired mucosal immune protection. Dimeric IgA molecules present on the basolateral side of epithelial cells are able to bind to basolateral receptors (poly-Ig receptors) on the epithelial cell and, via transcytosis, are presented on the apical side of the mucosal cell. On the mucosal surface, dimeric IgA is able to bind microorganisms and prevent them from entering the epithelial cells. Cleavage of IgA hinge regions impairs the antibody from performing this function. Illustration A displays a gram stain of N. gonorrhoeae. Note the gram negative diplococci. Incorrect Answers: Answer 1: S. pyogenes M protein impairs membrane attack complex formation which has no relationship to IgA protease. Answer 2: Opsonization and phagocytosis inhibition is an example of many different bacterial virulence factors but not those seen in Neisseria species. Answer 3: Impaired adaptive immune system memory is not a result of Neisseria species virulence factors. Answer 4: Neisseria species virulence factors do not Impair antibody binding to mast cells.
4.1
(9)
Please Login to add comment