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Liquefactive necrosis
15%
17/115
Cystic spaces
51%
59/115
Lymphocytic infiltrate
18%
21/115
Immune complex deposition
7%
8/115
Branching papillae
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This patient has a craniopharyngioma. These tumors typically exhibit dystrophic calcification, cyst formation, and hemorrhage. Craniopharyngioma is a benign pituitary tumor derived from the remnants of Rathke's pouch and is the most common cause of hypopituitarism in children. The tumor is typically suprasellar but can extend into the sella turcica and damage the pituitary gland. Craniopharyngioma causes bitemporal hemianopia and can cause central diabetes insipidus (preventing ADH release from the posterior pituitary). Illustration A depicts the characteristic cystic spaces and calcification in a craniopharyngioma. Incorrect Answers: Answer 1: Liquefactive necrosis is more commonly associated with focal bacterial or fungal infections. Answer 3: Lymphocytic infiltration is a characteristic finding in inflammatory conditions. Answer 4: Immune complex deposition is seen with a type III hypersensitivity reaction. Answer 5: Branching papillae are more consistent with papillary fibroelastoma (primary tumor of the heart).
3.6
(10)
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