Carbidopa is a medication used in the management and treatment of Parkinson disease (PD). It is in the decarboxylase inhibitor class of drugs. This activity reviews the indications, action, and contraindications for carbidopa as a valuable agent in the management of PD symptoms. This activity will highlight the mechanism of action, adverse event profile, and other key factors pertinent to members of the interprofessional team in the management of patients with PD and related conditions.