Kwashiorkor Causes protein-deficient diet Presentation skin lesions pitting edema ↓ albumin leads to ↓ oncotic pressure in vasculature and loss of fluid into extravascular space ascites liver malfunction ↓ apolipoprotein synthesis fatty liver defects in cell-mediated immunity ↓ in complement protein synthesis muscle protein relatively unchanged Marasmus Causes protein- and caloric-deficient diet Presentation tissue and muscle wasting "broomstick" extremities breakdown of muscle protein for energy loss of subcutaneous fat variable edema