Updated: 4/30/2015

Fibrocystic Change

Topic
Review Topic
0
0
Snap Shot
  • A 28-year-old female recently discovered a lump in her right breast. She has no family history of breast cancer, and her menstrual cycle began at 13 years of age. On exam you find a 1-cm movable mass in the right outer/upper quadrant. There is no skin dimpling. A mammogram is shown.
Introduction
  • Most common cause of benign breast masses in premenopausal women
  • Caused by exaggerated response to hormones and fluctuations in mass size
  • Not typically associated with progression to cancer
  • Several histologic types
    • fibrosis
      • breast stromal hyperplasia
    • cystic
      • may show large or small cysts
        • "blue domed"
      • ductal dilation
    • sclerosing adenosis
      • acini proliferation with intralobular fibrosis
      • associated with calcifications
      • commonly mistaken for infiltrating ductal cancer
    • ductal/epithelial hyperplasia
      • epithelial cell proliferation in terminal duct lobule
      • ↑ risk of carcinoma with atypical cells secondary to estrogen stimulation
Presentation
  • Symptoms
    • bilateral breast pain or tenderness
      • size/pain varies with the menstrual cycle
 

Please rate topic.

Average 4.0 of 2 Ratings

Thank you for rating! Please vote below and help us build the most advanced adaptive learning platform in medicine

The complexity of this topic is appropriate for?
How important is this topic for board examinations?
How important is this topic for clinical practice?
Topic COMMENTS (3)
Private Note