Updated: 12/6/2016

Misoprostol

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Misoprostol
  • Mechanism
    • PGE1 analog
    • ↑ production and secretion of HCO3- and mucus in mucous barrier
    • ↓ HCl secretion
  • Clinical use
    • treatment/prevention of NSAID-induced peptic ulcers
    • maintenance of a patent ductus arteriosus in congential heart abnormalities
    • abortifacient/labor induction
  • Toxicity
    • diarrhea
    • abortifacient action in women
 

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