Updated: 8/18/2016

Maturity Onset Diabetes of the Young (MODY)

Topic
Review Topic
0
0
Introduction
  • Diabetic symptoms as result of genetic mutations in metabolic transcription factor genes
    • many different loci have been identified
    • often involve glucose-sensing mechanisms in the pancreas
  • AD inheritance
  • Patients typically < 25 years
  • No association with obesity
  • No defect in insulin sensitivity - only insulin release
Evaluation
  • Serology
    • mild to severe hyperglycemia
    • do not see ketosis
Treatment
  • Medical
    • sulfonylureas
    • insulin
    • adjunctive diabetic agents
Prognosis, Prevention, and Complications
  • May progress to type II DM
 

Please rate topic.

Average 3.5 of 2 Ratings

Thank you for rating! Please vote below and help us build the most advanced adaptive learning platform in medicine

The complexity of this topic is appropriate for?
How important is this topic for board examinations?
How important is this topic for clinical practice?
Topic COMMENTS (6)
Private Note