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Review Question - QID 213860

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QID 213860 (Type "213860" in App Search)
A 38-year-old Caucasian man calls you for advice after a home genetic test reveals that he is a carrier of the F508del mutation in the CFTR gene on chromosome 7. He and his wife are trying to have a baby, but he is now worried that their future child could be at risk for cystic fibrosis. He tells you that his wife is healthy and has Ashkenazi Jewish ancestry. Given that 1 in 2300 Ashkenazi Jews are affected with cystic fibrosis, what is the chance that their child will have CF?