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Review Question - QID 213739

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QID 213739 (Type "213739" in App Search)
A 35-year-old man presents to his primary care physician with hematuria and dysuria. His past medical history is notable for 2 prior urinary tract infections, hypertension, and a cerebral aneurysm (treated with endovascular coil 1 year ago). The patient's father passed away at age 40 from renal failure. His mother is alive and healthy. On physical exam, the patient has mild abdominal distension and suprapubic tenderness. Urinalysis is positive for leukocyte esterase, white blood cells, and bacteria. Urine culture grows Escherichia coli. Further testing in this patient would likely reveal a mutation in which of the following genes?