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Review Question - QID 109850

Waterhouse-Friderichsen Syndrome Introduction Typically follows Neisseria meningitidis septicemia QID: 109850 (M1.EC.17.4871)
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QID 109850 (Type "109850" in App Search)
A 28-year-old male presents to the emergency room for severe malaise and fever. He reports developing a fever 10 hours prior to presentation that he initially attributed to a minor cold. Over the past 10 hours, he rapidly developed worsening chills, malaise, and a skin rash. Immediately after presenting to the emergency room, he becomes unconscious. His temperature is 102°F (38.9°C), blood pressure is 95/55 mmHg, pulse is 130/min, and respirations are 22/min. On examination he is pale, diaphoretic, and unresponsive. A diffuse skin rash is shown in Figure A. His fingers and toes appear cyanotic. Rapid intravenous fluid resuscitation and broad-spectrum antibiotics are initiated. A comprehensive laboratory workup is pending. Despite appropriate treatment, he remains unresponsive and passes away several hours later. This patient’s condition is caused by a pathogen that is characterized by which of the following?
  • A
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  • A