Review Question - QID 109768

A 64-year-old man presents to his primary care clinic for a regular checkup. He reports feeling depressed since his wife left him 6 months prior and is unable to recall why she left him. He denies any sleep disturbance, change in his eating habits, guilt, or suicidal ideation. His past medical history is notable for hypertension, gout, and a myocardial infarction five years ago. He takes lisinopril, aspirin, metoprolol, and allopurinol. He has a 50 pack-year smoking history and was previously a heroin addict but has not used in over 20 years. He drinks at least 6 beers per day. His temperature is 98.6°F (37°C), blood pressure is 155/95 mmHg, pulse is 100/min, and respirations are 18/min. He appears somewhat disheveled, inattentive, and smells of alcohol. During his prior visits, he has been well-groomed and attentive. When asked what year it is and who the president is, he confidently replies “1999” and “Jimmy Carter.” He says his son’s name is “Peter” when it is actually “Jake.” This patient likely has a lesion in which of the following brain regions?