Review Question - QID 109710

A 56-year-old man presents to the emergency department with severe epigastric pain that began an hour prior to presentation. He describes the pain as sharp, 10/10 in severity, and radiating to the back. Swallowing worsens the pain and causes him to cough. Before the pain started, he had been vomiting multiple times per day for the past week. The emesis was yellow and he denied ever seeing blood. Medical history is significant for poorly controlled hypertension, type II diabetes, alcohol use disorder, and 2 prior hospitalizations for acute pancreatitis. He smokes 1 pack of cigarettes per day for the last 35 years, denies illicit drug use, and drinks 3 pints of vodka per day. On physical exam, there is mediastinal crackling in synchrony with cardiac contraction on cardiac auscultation in the left lateral decubitus position. Laboratory testing is significant for leukocytosis. Which of the following is most likely the cause of this patient’s symptoms?