Review Question - QID 109444

A 58-year-old man presents to the emergency department with worsening shortness of breath, cough, and fatigue. He reports that his shortness of breath was worst at night, requiring him to sit on a chair in order to get some sleep. Medical history is significant for hypertension, hypercholesterolemia, and coronary heart disease. His temperature is 98.8°F (37.1°C), blood pressure is 146/94 mmHg, pulse is 102/min, respirations are 20/min with an oxygen saturation of 89%. On physical examination, the patient's breathing is labored. Pulmonary auscultation reveals crackles and wheezes, and cardiac auscultation reveals an S3 heart sound. After appropriate imaging and labs, the patient receives a non-rebreather facemask, and two intravenous catheters. Drug therapy is initiated. Which of the following is the site of action of the prescribed drug used to relieve this patient's symptoms?