Review Question - QID 109431

A 52-year-old man is brought to the emergency department after being found by police confused and lethargic in the park. The policemen report that the patient could not recall where he was or how he got there. Medical history is significant for multiple prior hospitalizations for acute pancreatitis. He also has scheduled visits with a psychiatrist for managing his depression and substance abuse. On physical examination, the patient was found to have horizontal nystagmus and a wide-based gait with short-spaced steps. The patient is started on appropriate medication and admitted to the medicine floor. He was re-evaluated after treatment implementation and currently does not appear confused. When asked how he got to the hospital, the patient says, "I remember leaving my wallet here and thought I should pick it up." On cognitive testing the patient is noted to have impairments in judgement, sequencing tasks, and memory. Which of the following enzymes was most likely impaired in this patient?