Review Question - QID 109423

A 53-year-old male presents to his primary care physician complaining of fatigue and joint and muscle pain. He reports a 6-month history of slowly progressive tiredness associated with dull achy pain in his knees, hips, and shoulders. His past medical history is notable for hypertension, diabetes, and stable angina. He takes lisinopril, metformin, glyburide, and aspirin. He has a history of intravenous drug use and was homeless in his early 30’s. He drinks alcohol socially and has a 30 pack-year smoking history. His temperature is 98.6°F (37°C), blood pressure is 130/85 mmHg, pulse is 95/min, and respirations are 18/min. Physical examination reveals a generally well-appearing male without evidence of ascites, peripheral edema, or jaundice. Results from laboratory tests are below:

Hepatitis A IgM: Negative
Hepatitis A IgG: Negative
Hepatitis B surface antigen: Negative
Hepatitis B E antigen: Negative
Hepatitis B core antigen: Negative
Hepatitis B surface IgG: Positive
Hepatitis B E IgG: Negative
Hepatitis B core IgG: Negative
Hepatitis C IgG: Positive
HCV RNA: 100,000,000 IU/ml

This patient should be started on which of the following medications?