Review Question - QID 109403

A 2-year-old boy is brought to the emergency department by his parents after they found him to be lethargic and febrile. His current symptoms started 1 week ago and initially consisted of a sore throat and a runny nose. He subsequently developed a fever and productive cough that has become worse over time. Notably, this patient has previously presented with pneumonia and gastroenteritis 8 times since he was born. On presentation, the patient's temperature is 103°F (39.4°C), blood pressure is 90/50 mmHg, pulse is 152/min, and respirations are 38/min. Based on clinical suspicion, an antibody panel is obtained and the results show low levels of IgG and IgA relative to the level of IgM. The expression of which of the following genes is most likely abnormal in this patient?