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Review Question - QID 109310

Principles of Neoplasia Steps of neoplastic progression Invasive carcinoma QID: 109310 (M1.ON.17.4799)
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QID 109310 (Type "109310" in App Search)
A 75-year-old female comes to the physician’s office with complaints of right lower quadrant pain. She has been experiencing these symptoms for the last 6 months and they have progressively gotten worse. An ultrasound reveals a large ovarian mass and abdominal and pelvic CT reveals no metastases. Her serum levels of CA-125 are elevated and the biopsy reveals the primary neoplasm as ovarian in origin. Her cancer is characterized as invasive carcinoma without metastasis. Which of the following cellular changes is consistent with this diagnosis?
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