Review Question - QID 109281

A 48-year-old homeless male presents to the ED because he hasn’t felt well recently. He states that he has been feeling nauseous and extremely weak over the past few days. He has several previous admissions for alcohol intoxication and uses heroin occasionally. His temperature is 100.9°F (38.3°C), blood pressure is 127/89 mmHg, and pulse is 101/min. His physical examination is notable for palmar erythema, tender hepatomegaly, and gynecomastia. His laboratory findings are notable for:

AST: 170 U/L
ALT: 60 U/L
GGT: 400 (normal range: 0-45 U/L)
Alkaline phosphatase: 150 IU/L
Direct bilirubin: 0.2 mg/dL
Total bilirubin: 0.8 mg/dL
WBC: 10,500
Serum iron: 100 µg/dL
TIBC: 300 µg/dL (normal range: 250–370 µg/dL)
Serum acetaminophen screen: Negative
Serum AFP: 6 ng/mL (normal range: < 10ng/mL)

Which of the following is the most likely cause of this patient’s symptoms?