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Review Question - QID 108967

Leukocyte Extravasation Introduction Step Molecule on Vasculature/Stroma Molecule on Leukocyte 1. Loose adhesion, rolling  E-selection, P-selectin Sialyl Lewis  2. Tight adhesion  ICAM-1 LFA-1 (integrin) 3. Diapedesis  PECAM-1 PECAM-1 4. Migration through ECM  Bacterial produ QID: 108967 (M1.PA.17.4754)
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QID 108967 (Type "108967" in App Search)
A 25-year-old G1P0 female of Middle Eastern descent gives birth to a male infant at 38 weeks’ gestation. The child is in the 15th percentile for both height and weight. Over the course of the first six months of the child’s life, he develops multiple severe skin and mucosal infections characterized by dramatically elevated white blood cell counts. The patient also demonstrates mental retardation soon after birth. A thorough hematologic analysis via flow cytometry reveals that the child's neutrophils that lack Sialyl-Lewis X. Which of the following processes is likely deficient in this patient?
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