Review Question - QID 108443

A 45-year-old female who recently immigrated to the United States presents to the community health clinic for episodes of disrupted vision. She is concerned because she knows several people from her hometown who went blind after having these episodes. Over the past several months, she also has developed itchy bumps on her back and lower extremities. Physical exam reveals black hyperpigmented nodules with edema and palpable lymphadenopathy, but is otherwise unremarkable without any visible discharge from the eyes. Her physician explains her underlying disease was likely transmitted by black flies. Which of the following is the most appropriate pharmacotherapy for this patient?