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Review Question - QID 106662

Severe Combined Immunodeficiency Disorder (SCID) Introduction Pathogenesis QID: 106662 (M1.IM.15.74)
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QID 106662 (Type "106662" in App Search)
A 2-month-old girl is brought to the pediatrician by her concerned father. He states that ever since her uncomplicated delivery she has failed to gain weight, has had chronic diarrhea, and has had multiple bacterial and viral infections. During the course of the workup, an absent thymic shadow is noted and a lymph node biopsy demonstrates the absence of germinal centers. Which of the following is the most likely cause of this patient's symptoms?
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