Snap Shot
  • A 28-year-old female presents with a 2 cm lump in the upper outer quadrant of her left breast. The mass changes in size in keeping with her menstrual cycle.
  • Several types
    • fibroadenoma
      • most common tumor in women < 35
      • benign lesion that does not progress to breast cancer
      • size and tenderness varies with estrogen changes 
      • histology shows hypercellular stroma that encircles or compresses ducts 
    • intraductal papilloma
      • small tumor 
      • typically beneath areola in lactiferous sinuses
      • common cause of bloody nipple discharge
    • phyllodes tumor
      • most common in post-menopausal women
      • consists of connective tissue and cysts with "leaf-like" projections
        • derived from stromal cells
      • may progress to malignancy
  • Fibroadenoma
    • palpable as a small, mobile, well circumscribed and firm mass
  • Intraductal papilloma
    • serous or bloody nipple discharge
  • Phyllodes tumor
    • large, bulky mass
  • Fine needle aspiration of the mass 

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