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 Bugs Causing Infection in HIV+ Adults

Bacteria
Disease Notes
Mycobacterium avium-intracellulare TB-like Especially CD4 < 50
Bartonella henselae Bacillary angiomatosis Superficial vascular proliferation
Virus
Disease Notes
CMV CMV retinitis, pneumonia "Cotton-wool spots" on fundoscopic exam in retinitis, Cowdry type A intranuclear inclusion bodies
EBV Oral hairy leukoplakia (OHL), Non-Hodgkin's lymphoma   --
HPV Squamous cell carcinoma Anus or cervix
HHV-8 Kaposi's sarcoma  --
JC virus Progressive multifocal leukoencephalopathy (PML) White matter damage in CNS, demyelination
Fungi
Disease Notes
Histoplasma capsulatum Histoplasmosis (pneumonia), hepatosplenomegaly, fever Disseminated disease only in immunocompromised
Candida albicans Thrush, esophagitis White plaque on oral mucosa
Cryptococcus neoformans Meningitis, encephalitis Most common meningitis in AIDS
Aspergillus fumigatus Invasive aspergillosis Pleuritic pain, hemoptysis
Pneumocystis jiroveci "PCP" ("P. carinii" pneumonia) Especially CD4 < 200
Protozoa
Disease Notes
CryptosporiDium Diarrhea Acid-fast cysts in stool
Toxoplasma gondii Brain abscesses Ring-enhancing lesions 
 

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