• Autoantibody against a coagulation factor
  • Anti-Factor VIII is the most common
    • recall factor VIII is deficient in hemophilia A
  • Symptoms
    • hemarthroses
    • intramuscular bleeding
    • GI bleeding
    • excessive bleeding in response to minor trauma
      • indistinguishable from hemophilia
  • Labs
    • PTT
    • normal PT, bleeding time
  • Mixing studies
    • supplied factor does not result in clot formation
      • antibody inhibits supplied factors
    • used to distinguish from hemophilia, which would clot when supplied normal plasma

Please rate topic.

Average 5.0 of 4 Ratings

Topic COMMENTS (6)
Private Note